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Murphy Lab - Research Projects


Descriptions of Past Projects

The most recent descriptions of our work can be found in papers on the publications page. The descriptions of the projects below are maintained for historical reference.

Interpretation of Protein Location Patterns from Fluorescence Microscope Images

Objective Comparison of Biomedical Imaging Experiments
(Edward J. S. Roques, Graduate Student in Biological Sciences)
Extracting and Classifying Fluorescence Microscope Images of Cells from Online Journals
(Jie Yao, Graduate Student at the Center for Automated Learning and Discovery, and Meel Velliste, Graduate Student in Biomedical Engineering)
Automated Classification of Protein Location Patterns from Fluorescence Microscopy: Phase 3 - Classification of 3-Dimensional Protein Location Patterns
(Meel Velliste, Graduate Student in Biomedical Engineering, and Aaron Rising, Undergraduate Student in Biological Sciences)
Automated Classification of Protein Location Patterns from Fluorescence Microscopy: Phase 4 - Object-level Recognition of Protein Subcellular Location Patterns
(Meel Velliste, Graduate Student in Biomedical Engineering, and Michael V. Boland, former Graduate Student in Biomedical Engineering)
Source and Resolution Independent Classification of Protein Location Patterns in Fluorescence Microscope Images
(Gregory Porreca, former Student in the Summer Undergraduate Research Program, and Meel Velliste, Graduate Student in Biomedical Engineering)
Methods for the objective selection of representative fluorescence microscope images: TypIC2
(Jennifer Lin, Undergraduate Student in Biological Sciences, James A. Gajnak, former Undergraduate in Biological Sciences and Computer Science, and Michael V. Boland, former Graduate Student in Biomedical Engineering)
Building Multimedia Knowledge Bases of Protein Subcellular Location Information
(Kai Huang, Graduate Student in Biological Sciences, and Jennifer Lin, Undergraduate Student in Biological Sciences)

Endosomal pH Regulation in Erythroid and Non-Erythroid Cells

References to Literature describing Differences in Endosomal pH between Cell Types

Endosomal pH Regulation

(Jeong-Ah Kwon, Graduate Student in Biological Sciences)


Interpretation of Protein Location Patterns from Fluorescence Microscopy

Automated Classification of Protein Location Patterns from Fluorescence Microscopy: Phase 1 - Resolution of Five Classes of Patterns in Chinese Hamster Ovary Cells
(Michael V. Boland, former Graduate Student in Biomedical Engineering,and Mia K. Markey, former Undergraduate in Biological Sciences)
Automated Classification of Protein Location Patterns from Fluorescence Microscopy: Phase 2 - Extension to Ten Classes of Patterns in HeLa Cells and Resolution of Similar Patterns
(Michael V. Boland, former Graduate Student in Biomedical Engineering)
Methods for the objective selection of representative fluorescence microscope images
(Mia K. Markey, former Undergraduate in Biological Sciences, and Michael V. Boland, former Graduate Student in Biomedical Engineering)

Endosomal pH Regulation in Erythroid and Non-Erythroid Cells

References to Literature describing Differences in Endosomal pH between Cell Types

Theoretical Modeling of Endosomal pH Regulation

(Sheree L. Rybak, former Graduate Student in Biological Sciences, in collaboration with Dr. Fred Lanni, Associate Professor of Biological Sciences)

Genes required for Receptor Recycling after Endocytosis

Identification of Genes Capable of Rescuing the Temperature-Conditional Defects in the End6 mutant of Chinese Hamster Ovary Cells
(E. John Meharra, former Graduate Student in Biological Sciences, Jeong-Ah Kwon, Graduate Student in Biological Sciences, and Yue Mary Yang, former Undergraduate in Biological Sciences)



Last Updated: 09 Jul 2009




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